Accumulation of free radical induced aging theory is very rich
experimental evidence for some long-standing unexplained phenomenon of
aging provides a strong theoretical basis to explain the other
theories can not explain the problems of aging, senescence theory for
many of the most abundant species , comprehensive and results emerging
new doctrine. It must be noted that although the vast majority of
research data are in support of free radical induced aging theory, but
there are a lot of information to conflicting or negative attitude.
Should see the resulting decline are complex, and not a small number
of genes or by interfering with biochemical processes can effectively
delay aging, nor is supplemented by a certain kind of antioxidant
activity, total antioxidant capacity is the steady state, when
artificially increase the level of a particular antioxidant, the other
will be compensatory antioxidant capacity to decline, eventually
bringing the total antioxidant capacity can not achieve the desired
change. Since people did not increase the total antioxidant Hua Liping
find an effective way. Geriatric long way to go, but it is full of
hope. You forward to the birth of Dolly the cloned sheep (Dolly is a
6-year-old ewe to provide the nucleus of breast cells, injected into
the enucleated egg cell from the clone. 6 negative sheep equivalent to
30-year-old who is the sheep to middle age! cloned Dolly the past
decades after the 6-year-old ewe by youth, live enough to later years,
or live by the middle-aged mortality from the halfway, which has
become a geriatric concerns), as biotechnology advances to move
forward, extending the maximum human life is ultimately so that a
better knowledge and experience accumulated, and promote further
progress of human civilization.
4. Theory of aging are more than three hundred kinds, reflecting the
factors that cause aging are not single, but the decision by many
factors, free radicals, but is a factor of a lot of work, but it
caused a considerable decline in the play but important role. So far
this theory has been very rich and strong evidence. Although other
theories of aging and the strengths of their theoretical basis,
gallbladder isolated some theories emphasize one aspect of Fox, or
some conflict between the doctrine that only the free radical theory
can be linked to many theories become the center of many theories.
Human memory in a clear radical defense system, mainly by the
superoxide dismutase (SOD) and peroxidase. Older cells, anti-free
radical activity decreased, the dangers of free radicals that
significantly enhanced. Antioxidant vitamins C and E also has
anti-free radicals. Harman 1956, the first American scholars free
radicals can cause aging put forward the idea, then as the deepening
of research, has formed a relatively systematic "free radical theory."
The doctrine that: in the normal metabolic processes of cell biology
continue to produce free radicals, but they may be the intracellular
defense system quickly removed, and thus will not cause significant
damage to the cells. However, many factors such as ionizing radiation,
oxidative and environmental pollution often induced by abnormal
production of free radicals and accumulation, while a large
accumulation of free radicals will be for many biological
macromolecules and cells of the stochastic damage, which lead to
apoptosis.
